Lisinopril is a common ACE inhibitor that doctors prescribe for high blood pressure and heart conditions. It brings your blood pressure down by preventing your body from producing as much angiotensin II, a hormone that causes blood vessels to narrow.
If you’re taking lisinopril, you may be concerned about potential side effects, particularly regarding your sexual health. Can lisinopril affect testosterone? Does it cause erectile dysfunction? We’ll explore the relationship between lisinopril and testosterone in this article.
How Lisinopril Works
Lisinopril is an ACE inhibitor, meaning it affects the Renin-Angiotensin System (RAS). The RAS system helps control blood pressure.
Lisinopril works by blocking the conversion of angiotensin I to angiotensin II. Angiotensin II narrows your blood vessels, so blocking its production leads to vasodilation (widening of the blood vessels) and, ultimately, lower blood pressure. The RAS system has a lot of other implications for overall health, too.
Lisinopril and Erectile Dysfunction (ED): Is There a Connection?
Erectile dysfunction is listed as a potential side effect of lisinopril. However, it’s not a common side effect. Some studies even suggest lisinopril might improve ED symptoms by helping blood flow more freely.
ED can stem from many things besides medication. Other medications, underlying health conditions like diabetes, and mental health conditions like anxiety or depression may be responsible. Some men also find that coffee benefits them sexually.
Lisinopril’s Impact on Testosterone Levels: Examining the Evidence
Does lisinopril affect testosterone? Researchers have looked at this question, and the answer isn’t totally clear.
A 1998 study by Koshida and colleagues found that lisinopril may decrease plasma free testosterone in men with high blood pressure and increase sex hormone-binding globulin in women with hypertension.
Other studies have shown that using ACE inhibitors like lisinopril may be associated with lower levels of dehydroepiandrosterone in older men.
Another study showed that blocking the renin-angiotensin system may reduce serum free testosterone in middle-aged men who are on dialysis.
Sex Hormone Binding Globulin (SHBG)
SHBG is a protein that binds to testosterone. When testosterone is bound to SHBG, it’s not “free” to be used by the body. So, SHBG levels can affect how much testosterone is available to your body.
That’s why, when doctors check your hormone levels to determine your risk for heart and blood vessel disease, they should check SHBG levels along with androgen and estrogen levels.
Lisinopril vs. Other Blood Pressure Meds
Lisinopril isn’t the only ACE inhibitor out there; enalapril, ramipril, and benazepril are others that work in much the same way and carry similar potential side effects. It’s also worth remembering that different blood pressure medications, in general, can have different effects on sexual function.
One more thing to consider: some studies have suggested that ACE inhibitors like lisinopril might slightly increase bone loss in older men, while angiotensin receptor blockers (ARBs) might not have this effect. Talk to your doctor about what’s right for you.
What to do if you experience ED while taking lisinopril
If you experience erectile dysfunction while taking lisinopril, the most important thing you can do is talk to your doctor. Give them a complete list of all medications you’re taking. Sometimes ED symptoms resolve on their own as your body adjusts to the medication.
It’s also important to manage any underlying health conditions that might be contributing to ED. Your doctor can help you determine the best course of action.
Frequently Asked Questions
What is the biggest side effect of lisinopril?
One of the most commonly reported side effects of lisinopril is a persistent dry cough. Other potential side effects include dizziness, lightheadedness, and headache, especially when starting the medication or increasing the dosage.
What blocks testosterone absorption?
Several factors can potentially interfere with testosterone levels or its effects in the body. These can include certain medications (like opioids or corticosteroids), medical conditions (such as obesity or type 2 diabetes), and lifestyle factors (like chronic stress or excessive alcohol consumption). However, it’s important to note there is no evidence that lisinopril blocks testosterone absorption.
What does lisinopril do to men?
Lisinopril is primarily used to treat high blood pressure and heart failure in both men and women. It works by relaxing blood vessels, which allows blood to flow more easily and reduces strain on the heart. While rare, some men taking lisinopril may experience sexual side effects.
Can I take Viagra with lisinopril?
It’s generally considered safe to take Viagra (sildenafil) with lisinopril, but it’s essential to discuss this with your healthcare provider first. Both medications can lower blood pressure, and combining them may increase the risk of dizziness or lightheadedness. Your doctor can assess your individual risk and provide personalized recommendations.
What organs does lisinopril affect?
Lisinopril primarily affects the cardiovascular system, specifically the blood vessels and the heart. It can also impact the kidneys, as it influences blood flow and pressure within the kidneys. Regular monitoring of kidney function is often recommended during lisinopril treatment.
Key Takeaways
Research on how lisinopril affects testosterone is mixed. Erectile dysfunction isn’t always caused directly by this medication.
It’s important to take a well-rounded approach to your health, keeping both your cardiovascular health and your sexual well-being in mind.
If you have concerns, talk openly with your healthcare provider. Together, you can find solutions that work for you.