Testosterone is a hormone that’s important for male health, but it is important to consider other medications, like steroids and antibiotics, when evaluating overall health. It affects a lot of functions throughout the body. But not all testosterone is created equal. Your body produces testosterone naturally. This is called endogenous testosterone. You can also get testosterone from external sources like hormone therapy. This is considered non-endogenous testosterone.
When your body uses testosterone, it breaks it down into other substances called metabolites. Two important metabolites are dihydrotestosterone (DHT) and estradiol (E2). These metabolites also play key roles in the body.
There’s a lot of debate about whether testosterone therapy is good or bad for your heart. Some studies suggest it could increase the risk of heart problems. Others say it has little or no effect.
This article will focus on non-endogenous testosterone metabolites and how they might affect your cardiovascular health. We’ll look at studies that have examined the link between non-endogenous testosterone, its metabolites like DHT and E2, and cardiovascular events. Our goal is to give you a clear picture of what we currently know about these connections.